SLU-PP-332 Capsules

Product Description

Quick Specifications

• Content: 250 mcg SLU-PP-332 per capsule (100 capsules total)
• Form: Research capsules
• Chemical Formula: C₁₈H₁₄N₂O₂
• Molecular Weight: 290.3 g/mol
• CAS Number: 303760-60-3
• Alternative Names: 4-Hydroxy-N'-(naphthalen-2-ylmethylene) benzohydrazide
• Purity: >99%

Research Applications & Mechanisms

SLU-PP-332 is a breakthrough estrogen-related receptor (ERR) agonist that targets ERRα and ERRγ receptors. This compound represents the first viable "exercise mimetic" - a substance that can replicate many benefits of physical exercise at the cellular level without requiring actual exercise.

Exercise Mimetic Properties SLU-PP-332 activates the same cellular pathways that respond to exercise stress. It increases mitochondrial density and function, particularly in heart and skeletal muscle cells. Animal studies show mice given SLU-PP-332 can run 70% longer and 45% further than controls, demonstrating significant endurance enhancement without training.

The compound works by targeting "orphan" nuclear receptors called ERRs, which control genes involved in energy production, fat burning, and mitochondrial creation. These receptors naturally respond to exercise but can be activated directly by SLU-PP-332.

Metabolic Research Applications Studies demonstrate SLU-PP-332 increases energy expenditure primarily through enhanced fat burning. Mice given the compound twice daily for one month lost 12% of body weight without changes in food intake or exercise habits. The compound helps treat metabolic syndrome by improving how cells use oxygen and nutrients.

SLU-PP-332 enhances the switch from sugar burning to fat burning that normally occurs during endurance exercise. This metabolic flexibility is crucial for sustained energy production and weight management.

Mitochondrial Function Enhancement The compound directly improves mitochondrial health - the cellular power plants that produce energy. It increases both mitochondrial number and efficiency, leading to better oxygen utilization and reduced cellular fatigue. This enhanced mitochondrial function explains the endurance and metabolic benefits.

ERR receptors control genes involved in mitochondrial creation, function, and repair. SLU-PP-332 activation leads to more efficient cellular energy production and reduced oxidative stress.

Cardiovascular Research SLU-PP-332 shows significant heart protection benefits. In heart failure models, it improves ejection fraction, reduces harmful fibrosis (scarring), and increases survival rates. The compound helps normalize fatty acid use by heart muscle and improves overall cardiac energy balance.

The compound also increases blood vessel density in skeletal muscle, improving nutrient delivery and waste removal. This enhanced blood flow contributes to better exercise tolerance and insulin sensitivity.

Neuroprotection Studies Research suggests SLU-PP-332 may help protect against Parkinson's disease. The targeted ERRγ receptors are essential for maintaining brain cell mitochondria and clearing damaged proteins. Parkinson's neurons are especially vulnerable to energy production problems, making ERR activation potentially protective.

The compound helps maintain normal autophagy - the cellular cleanup process that removes damaged components and prevents disease-causing protein buildup.

Anti-Aging Research Applications SLU-PP-332 mimics benefits of caloric restriction, one of the few proven anti-aging interventions. Studies show it protects kidney function, reduces inflammation markers, and maintains mitochondrial health during aging. The compound helps prevent the mitochondrial decline that contributes to cellular aging.

Age-related ERR receptor decline correlates with decreased energy production and increased cellular damage. SLU-PP-332 supplementation may help maintain youthful cellular energy levels.

Bioavailability & Research Advantages Unlike earlier ERR compounds that only worked in lab dishes, SLU-PP-332 reaches target tissues throughout the body when taken. This makes it valuable for whole-body metabolic research and exercise physiology studies.

The compound represents the first successful ERRα agonist developed, filling a critical gap in metabolic research tools. Its bioavailability and safety profile make it ideal for extended research protocols.

Storage Instructions Store in a cool, dry place away from direct light and moisture. Keep container tightly sealed. Protect from heat and humidity.

For Research Purposes Only This product is for laboratory research only by qualified scientists. Not for human use, medical treatment, or veterinary applications. Follow all safety protocols.