SS-31

Product Description

Overview

SS-31, also known as Elamipretide, is a small, aromatic peptide designed to penetrate mitochondria and stabilize cardiolipin, a crucial phospholipid in the inner mitochondrial membrane. By preserving cardiolipin function, SS-31 helps reduce the production of harmful reactive oxygen species (ROS) and enhances cellular energy production through improved ATP synthesis.

Physical Form

• Lyophilized powder in a sterile 3 mL vial

Peptide Structure

• Sequence: D-Arg-Tyr(2,6-diMe)-Lys-Phe
  
  
• Molecular Formula: C32H49N9O5
  
  
• Molecular Weight: 639.8 g/mol

Research Highlights

Mitochondrial Function & Disease

• Restores ATP production and reduces cell death in models of mitochondrial disease
  
  
• Approved orphan drug status and in clinical trials for mitochondrial myopathy and related disorders

Heart Health & Ischemia

• Improves mitochondrial respiration and cardiac function in heart failure models
  
  
• Reduces cardiomyocyte apoptosis in heart attack, preserving heart tissue

Diabetes & Oxidative Stress

• Decreases reactive oxygen species, reduces inflammation, and improves insulin sensitivity
  
  
• Increases SIRT1 levels linked to better metabolic control

Anti-Inflammatory Effects

• Regulates mitochondrial proteins linked to inflammation, including FIS1 and NF-kappaB
  
  
• Prevents inflammasome activation, maintaining healthy mitochondrial energy production

Important Notes

For research use only. Not intended for human consumption or medical/veterinary use.
Use appropriate safety protocols when handling this peptide.