MOTS-c

Product Description

Overview

MOTS-c is a naturally occurring mitochondrial-derived peptide (MDP) encoded within the mitochondrial genome. It plays a key role in regulating energy metabolism, insulin sensitivity, and cellular communication between mitochondria and the nucleus. MOTS-c is a promising candidate in research on metabolic health, weight regulation, exercise capacity, bone integrity, and aging.

Physical Form

• Lyophilized powder in a sterile 3 mL vial

Peptide Structure

• Sequence: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg
  
  
• Molecular Formula: C101H152N28O22S2
  
  
• Molecular Weight: 2174.64 g/mol

Research Highlights

Metabolic Regulation & Insulin Sensitivity

• Enhances muscle glucose uptake via AMPK activation independently of insulin pathways
  
  
• Reduces insulin resistance and promotes brown fat function, aiding weight management

Fat Metabolism & Energy Balance

• Activates methionine-folate cycle and beta-oxidation pathways to prevent fat accumulation
  
  
• Regulates nuclear gene expression linked to glucose restriction and antioxidant responses

Muscle & Bone Health

• Improves skeletal muscle function and growth through enhanced glucose utilization
  
  
• Stimulates osteoblast survival and bone formation via TGF-beta/SMAD signaling

Longevity & Cellular Health

• Linked to exceptional longevity in certain populations via genetic variations
  
  
• Supports mitochondrial function, potentially extending healthspan

Cardiovascular Benefits

• Improves endothelial function and microvascular health
  
  
• May protect cardiac cells from stress and inflammation

Important Notes

For research use only. Not intended for human consumption or medical/veterinary use.
Strictly follow safety and regulatory guidelines when handling.