Semax

Product Description

Quick Specifications

• Content: 5 mg Semax per vial
• Form: Sterile lyophilized powder in 3 mL glass vial
• Sequence: Ac-Met-Glu-His-Phe-Pro-Gly-Pro
• Molecular Formula: C₃₉H₅₄N₁₀O₁₀S
• Molecular Weight: 854.99 g/mol
• CAS Number: 80714-61-0
• Alternative Names: Pro-Gly-Pro-ACTH
• Purity: >99%

Research Applications & Mechanisms

Semax is a synthetic version of adrenocorticotropic hormone (ACTH) developed in Russia for brain research. This peptide contains amino acids 4-10 of ACTH and has shown promise in stroke recovery, cognitive improvement, and brain protection studies.

Brain Network Enhancement Brain imaging studies show Semax boosts the default mode network - brain areas active during rest. This network helps us stay aware of our surroundings and switch from rest to focused attention. It plays a key role in social thinking and environmental monitoring. Diseases like Alzheimer's often damage this network, making Semax valuable for brain health research.

Stroke & Brain Injury Research Semax is used in Russia to treat brain oxygen loss from strokes and head injuries. Animal studies show it changes 24 different genes that control blood vessel function in the brain. These genes help create new blood vessels, move nutrients, and form red blood cells. This may explain why Semax protects brain cells and helps them survive injury.

Human stroke studies show Semax speeds up recovery and improves final function levels. Patients get better faster and perform better on movement tests when given Semax during rehabilitation.

Learning & Memory Enhancement Semax increases brain-derived neurotrophic factor (BDNF), a protein that helps brain cells grow and connect. Within 20 minutes of use, it changes gene activity in the hippocampus (memory center) and frontal cortex (thinking center). This helps explain why Semax may improve learning and memory.

Research suggests Semax protects learning ability even during seizures. This makes it useful for studying how to maintain brain function during medical problems.

Cognitive Performance Studies Studies show Semax may boost thinking skills in healthy people, not just those with brain problems. It helps the brain make new connections and improves how different brain areas work together. This could lead to better problem-solving, memory, and creativity.

Depression & Mood Research Semax increases BDNF levels, which helps regulate mood. Current antidepressants may work by slowly increasing BDNF, which is why they take weeks to help. Semax might speed up this process by directly boosting BDNF. Research suggests combining Semax with standard depression treatments could work better and faster.

Gene Expression & Brain Function A single dose of Semax affects gene activity in key brain areas within minutes. It particularly boosts nerve growth factor (NGF) and BDNF production. These changes help brain cells grow, repair, and make new connections. This makes Semax valuable for studying how the brain adapts and heals.

Immune & Cardiovascular Effects Research suggests Semax may boost immune function and improve heart health. It affects blood clotting and pain control systems. These effects show the peptide works throughout the body, not just in the brain.

Reconstitution & Storage Mix with bacteriostatic water. Once mixed, keep at 2-8°C and use within 30-60 days. Protect from light.

For Research Purposes Only This product is for laboratory research only by qualified scientists. Not for human use, medical treatment, or veterinary applications. Follow all safety protocols.